Biomonitoring equivalents: A screening approach for interpreting biomonitoring results from a public health risk perspective
نویسندگان
چکیده
منابع مشابه
Biomonitoring equivalents: a screening approach for interpreting biomonitoring results from a public health risk perspective.
Advances in both sensitivity and specificity of analytical chemistry have made it possible to quantify substances in human biological specimens, such as blood, urine, and breast milk, in specimen volumes that are practical for collection from individuals. Research laboratories led by the Centers for Disease Control and Prevention (CDC) in its series National Report on Human Exposure to Environm...
متن کاملInterpreting human biomonitoring data in a public health risk context using Biomonitoring Equivalents.
Human biomonitoring (HBM) has proven an extremely valuable tool for determining which chemicals are getting into people, detecting trends in population exposures over time, and identifying populations with exposures above background. The potential significance of the HBM data in the context of existing toxicology data and risk assessments can be assessed if chemical-specific quantitative screen...
متن کاملBiomonitoring Equivalents for bisphenol A (BPA).
Recent efforts worldwide have resulted in a growing database of measured concentrations of chemicals in blood and urine samples taken from the general population. However, few tools exist to assist in the interpretation of the measured values in a health risk context. Biomonitoring Equivalents (BEs) are defined as the concentration or range of concentrations of a chemical or its metabolite in a...
متن کاملBiomonitoring Data for 2,4-Dichlorophenoxyacetic Acid in the United States and Canada: Interpretation in a Public Health Risk Assessment Context Using Biomonitoring Equivalents
BACKGROUND Several extensive studies of exposure to 2,4-dichlorophenoxyacetic acid (2,4-D) using urinary concentrations in samples from the general population, farm applicators, and farm family members are now available. Reference doses (RfDs) exist for 2,4-D, and Biomonitoring Equivalents (BEs; concentrations in urine or plasma that are consistent with those RfDs) for 2,4-D have recently been ...
متن کاملThe use of biomonitoring equivalents for interpreting blood concentrations in population studies: a case for polychlorinated biphenyls
A number of exposure guideline values for environmental contaminants are established by various agencies for risk assessment purposes. Biomonitoring equivalents are conversions of external guideline values to internal doses, against which biomonitoring data can be directly compared. Several biomonitoring equivalents have been developed for the interpretation of blood concentrations of environme...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Regulatory Toxicology and Pharmacology
سال: 2007
ISSN: 0273-2300
DOI: 10.1016/j.yrtph.2006.08.004